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Guan Wang Selected Research

CUDC-907

1/2021Antitumor activity and mechanism of resistance of the novel HDAC and PI3K dual inhibitor CUDC-907 in pancreatic cancer.
1/2021The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia.
1/2020CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.
11/2019Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia.

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Guan Wang Research Topics

Disease

78Neoplasms (Cancer)
06/2022 - 06/2007
15Inflammation (Inflammations)
04/2022 - 11/2014
10Hepatocellular Carcinoma (Hepatoma)
04/2022 - 07/2011
10Breast Neoplasms (Breast Cancer)
11/2021 - 01/2014
10Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2021 - 02/2015
9Neoplasm Metastasis (Metastasis)
01/2022 - 01/2015
9Pancreatic Neoplasms (Pancreatic Cancer)
01/2021 - 01/2012
7Alzheimer Disease (Alzheimer's Disease)
01/2022 - 01/2010
6Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 04/2013
6Fibrosis (Cirrhosis)
07/2021 - 09/2014
6Lung Neoplasms (Lung Cancer)
01/2020 - 01/2013
5Stomach Neoplasms (Stomach Cancer)
06/2022 - 01/2020
5Triple Negative Breast Neoplasms
12/2021 - 01/2021
5Hypoxia (Hypoxemia)
03/2021 - 01/2018
5Infections
10/2020 - 01/2014
4Rheumatoid Arthritis
01/2022 - 01/2019
4Parkinson Disease (Parkinson's Disease)
01/2022 - 12/2018
4Neuroblastoma
01/2022 - 01/2013
4Cholangiocarcinoma
10/2020 - 01/2019
4Ovarian Neoplasms (Ovarian Cancer)
09/2020 - 01/2014
4Obesity
01/2020 - 04/2008
3Osteoarthritis
04/2022 - 10/2015
3Non-alcoholic Fatty Liver Disease
01/2022 - 01/2020
3Sepsis (Septicemia)
01/2022 - 01/2021
3Body Weight (Weight, Body)
01/2022 - 10/2012
3Heart Failure
01/2022 - 08/2010
3Hypertension (High Blood Pressure)
05/2021 - 01/2018
3Colorectal Neoplasms (Colorectal Cancer)
03/2021 - 01/2020
3Pain (Aches)
01/2021 - 07/2011
3Leukemia
08/2020 - 01/2014
3Glioma (Gliomas)
11/2018 - 06/2014
3Spinal Cord Injuries (Spinal Cord Injury)
01/2018 - 01/2016
3Carcinogenesis
08/2016 - 04/2013
2Diabetic Nephropathies (Diabetic Nephropathy)
02/2022 - 11/2014
2Autoimmune Diseases (Autoimmune Disease)
01/2022 - 11/2021
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 01/2018
2Huntington Disease (Huntington's Disease)
01/2022 - 01/2022
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 01/2022
2Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis)
01/2022 - 01/2020
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2022 - 01/2022
2Peripheral Vascular Diseases (Peripheral Vascular Disease)
12/2021 - 01/2021

Drug/Important Bio-Agent (IBA)

28Proteins (Proteins, Gene)FDA Link
01/2022 - 09/2012
22Pharmaceutical PreparationsIBA
06/2022 - 01/2013
13Biological ProductsIBA
02/2022 - 07/2010
8MicroRNAs (MicroRNA)IBA
06/2022 - 01/2012
8Biomarkers (Surrogate Marker)IBA
05/2021 - 12/2015
7CytokinesIBA
12/2021 - 01/2019
7Histone Deacetylases (Histone Deacetylase)IBA
01/2021 - 01/2012
7DNA (Deoxyribonucleic Acid)IBA
01/2019 - 01/2013
6Glucose (Dextrose)FDA LinkGeneric
01/2022 - 05/2014
6Messenger RNA (mRNA)IBA
09/2020 - 06/2014
5venetoclaxIBA
01/2021 - 06/2016
5RNA (Ribonucleic Acid)IBA
01/2020 - 07/2011
4Phosphotransferases (Kinase)IBA
06/2022 - 05/2015
4Long Noncoding RNAIBA
04/2022 - 08/2016
4Blood Glucose (Blood Sugar)IBA
01/2022 - 01/2018
4NAD (NADH)IBA
12/2021 - 10/2019
4CUDC-907IBA
01/2021 - 11/2019
3Peptides (Polypeptides)IBA
06/2022 - 07/2010
3Photosensitizing Agents (Photosensitizers)IBA
05/2022 - 01/2022
3AntigensIBA
01/2022 - 12/2017
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022 - 05/2021
3ErbB Receptors (EGF Receptor)IBA
01/2022 - 01/2018
3CalciumIBA
01/2022 - 10/2012
3Insulin (Novolin)FDA Link
01/2022 - 10/2012
3LipidsIBA
05/2021 - 10/2012
3Indicators and Reagents (Reagents)IBA
01/2021 - 06/2019
3VaccinesIBA
10/2020 - 10/2018
3Protein Kinases (Protein Kinase)IBA
12/2018 - 10/2012
3Fluorouracil (Carac)FDA LinkGeneric
01/2016 - 01/2014
3Endoplasmic Reticulum Chaperone BiPIBA
05/2015 - 01/2013
3obatoclaxIBA
02/2015 - 06/2014
3PanobinostatIBA
01/2015 - 01/2013
2Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
06/2022 - 12/2018
2TropomyosinIBA
06/2022 - 02/2021
2Mitogen-Activated Protein Kinase 3IBA
05/2022 - 05/2016
2Therapeutic UsesIBA
02/2022 - 01/2021
2Bleomycin (Blenoxane)FDA LinkGeneric
02/2022 - 07/2021
2Cyclin-Dependent Kinases (cdk Proteins)IBA
02/2022 - 04/2013
2diazonaphthalenedisulfonic acid (NDS)IBA
01/2022 - 01/2022
2Propofol (Diprivan)FDA LinkGeneric
01/2022 - 03/2019
2Folic Acid (Vitamin M)FDA LinkGeneric
01/2022 - 10/2014
2NucleotidesIBA
01/2022 - 01/2020
2Superoxide DismutaseIBA
01/2022 - 05/2021
2Malondialdehyde (Propanedial)IBA
01/2022 - 05/2021
2LigandsIBA
01/2022 - 01/2013
2osimertinibIBA
01/2022 - 01/2018
2SirtuinsIBA
12/2021 - 01/2020
2Matrix Metalloproteinases (MMPs)IBA
11/2021 - 05/2021
2LeptinIBA
11/2021 - 10/2012

Therapy/Procedure

37Therapeutics
05/2022 - 08/2010
13Drug Therapy (Chemotherapy)
02/2021 - 01/2013
8Immunotherapy
01/2022 - 01/2019
3Aftercare (After-Treatment)
07/2021 - 07/2017
3Radiotherapy
03/2021 - 10/2014
3Transplantation
01/2018 - 04/2013
2Intraperitoneal Injections
02/2022 - 01/2018
2Lasers (Laser)
01/2022 - 11/2012
2Photothermal Therapy
01/2022 - 03/2021
2Ligation
12/2021 - 01/2021